circAtlas 2.0 An integrated resource of circRNAs in vertebrates.

Welcome to circAtlas 2.0

Circular RNAs (circRNAs) are a novel class of RNAs with important biological implications. Currently, a huge number of circRNAs was already identified from high-throughput RNA-seq data sets. However, functional annotation and prioritization of these circRNAs for further expreimental validation as well as functional investigation is the bottleneck step for current circRNA studies. Now, we developed a new resource database and web tool named circAtlas 2.0 that integrated over one millions of circRNAs across 6 species (human, macaca, mouse, rat, pig, chicken) and a variety of tissues. The circAtlas 2.0 can fill this gap by integrating the most comprehensive circRNAs and their expression and functional profiles in vertebrates, which provides a foundation for circRNA studies and serves as a powerful starting point to investigate their biological significance.

Dataset Summary

Homo sapiens
421,501 circRNAs
Macaca mulatta
169,618 circRNAs
Mus musculus
175,273 circRNAs

Rattus norvegicus
80,158 circRNAs

Sus scrofa
75,953 circRNAs
15 9
Gallus gallus
92,428 circRNAs

  Using circAtlas

        Browse circAtlas
                Choose species to browse all the circRNAs.
        Search circAtlas
                 Search circRNAs by ID, host gene or position.
        Conserved circRNAs
                Provide conservation information of circRNAs across different species.
        ID Converter
                Convert ID from different circRNA databases and assemblies.
        ORFs in circAtlas
                Predict potential open reading frames on circRNAs.
        IRES in circAtlas
                Predict Internal Ribosomal Entry Sites on circRNAs.
        RBP Binding
                Predict RBP binding sites on circRNAs.
        miRNA Binding
                Provide predicted miRNA binding sites of circRNA.
        Network annotation
                Annotate circRNA functions using gene co-expression network.
                Species-specific circRNAs provided in circAtlas.