circAtlas 2.0 An integrated resource of circRNAs in vertebrates.
Welcome to circAtlas 2.0
Circular RNAs (circRNAs) are a novel class of RNAs with important biological implications. Currently, a huge number of circRNAs was already identified from high-throughput RNA-seq data sets. However, functional annotation and prioritization of these circRNAs for further expreimental validation as well as functional investigation is the bottleneck step for current circRNA studies. Now, we developed a new resource database and web tool named circAtlas 2.0 that integrated millions of circRNAs across 7 species (human, macaca, mouse, rat, pig, chicken, dog) and a variety of tissues. The circAtlas 2.0 can fill this gap by integrating the most comprehensive circRNAs and their expression and functional profiles in vertebrates, which provides a foundation for circRNA studies and serves as a powerful starting point to investigate their biological significance.
1. 19 Mar 2019: Citation: Ji P, Wu W, et al. Zhao F. Expanded expression landscape and prioritization of circular RNAs in mammals. Cell Reports, 2019, 26: 3444–3460 2. 19 Mar 2019: The first version of circAtlas was moved to http://zhaolab.biols.ac.cn.
Browse circAtlas Choose species to browse all the circRNAs. Search circAtlas Search circRNAs by ID, host gene or position. Conserved circRNAs Provide conservation information of circRNAs across different species. ID Converter Convert ID from different circRNA databases and assemblies. ORFs in circAtlas Predict potential open reading frames on circRNAs.
IRES in circAtlas Predict Internal Ribosomal Entry Sites on circRNAs. RBP Binding Predict RBP binding sites on circRNAs. miRNA Binding Provide predicted miRNA binding sites of circRNA. Network annotation Annotate circRNA functions using gene co-expression network. Download Species-specific circRNAs provided in circAtlas.